Description

Ethyl 7-Chloro-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the quinolone carboxylic acid ester class. This compound is a critical building block in the synthesis of novel fluoroquinolone antibiotics, offering a strategic advantage for manufacturers developing next-generation antimicrobial agents. It is essential for R&D and production facilities in the global pharmaceutical and fine chemical industries seeking reliable, high-quality raw materials for complex API synthesis.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a core precursor in the synthesis of potent antibacterial agents like levofloxacin and other third/fourth-generation quinolones.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and structural modification of new antibacterial compounds with improved efficacy and safety profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in scaled-up GMP production processes for commercial antibiotic formulations.
• Fine Chemical Synthesis: Utilized as a versatile building block for creating complex heterocyclic compounds with potential biological activity beyond antibacterials.

Basic Information

Product Name	Ethyl 7-Chloro-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate
CAS No.	75073-15-3
Molecular Formula	C12H9ClFNO3
Molecular Weight	269.66 g/mol
Synonyms	7-Chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid ethyl ester; Ethyl 7-chloro-6-fluoro-4-oxo-1H-quinoline-3-carboxylate; 1,4-Dihydro-7-chloro-6-fluoro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 1,4-dihydro-7-chloro-6-fluoro-4-oxo-, ethyl ester; 75073-15-3; 7-Chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-6-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines and can provide material meeting specifications for use in GMP-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.