Description

7,8-Dichloro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its versatile halogenated and esterified structure, which provides a key scaffold for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including hydrolysis, amidation, and nucleophilic substitution reactions.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers and functional materials with specific optical or electronic properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in related manufacturing processes.

Basic Information

Product Name	7,8-Dichloro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	75001-53-5
Molecular Formula	C₁₂H₉Cl₂NO₃
Molecular Weight	286.11 g/mol
Synonyms	Ethyl 7,8-Dichloro-4-hydroxyquinoline-3-carboxylate; 7,8-Dichloro-4-hydroxy-3-quinolinecarboxylic Acid Ethyl Ester; 4-Hydroxy-7,8-dichloroquinoline-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-7,8-dichloro-4-hydroxyquinoline; 7,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; Ethyl 7,8-dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 7,8-Dichloro-4-Hydroxy-Quinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.