Description

5-Amino-1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-1H-Pyrazole-4-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its pyrazole core and electron-withdrawing substituents. This compound matters for its role as a critical synthetic intermediate in the development of advanced agrochemicals and pharmaceuticals, enabling the creation of molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern pesticides, herbicides, and fungicides, particularly those requiring a pyrazole scaffold for bioactivity.
• Pharmaceutical Research: Serves as a versatile building block for constructing novel drug candidates in medicinal chemistry programs, especially for targets involving enzyme inhibition.
• Dye and Pigment Synthesis: Used in the development of specialized dyes and organic pigments, leveraging its nitro and cyano groups for color and stability properties.
• Material Science: Employed in the research and production of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Synthesis: Functions as a sophisticated reagent for constructing complex heterocyclic systems in academic and industrial organic synthesis.

Basic Information

Product Name	5-Amino-1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-1H-Pyrazole-4-Carbonitrile
CAS No.	74990-43-5
Molecular Formula	C11H6F3N5O2
Molecular Weight	297.20 g/mol
Synonyms	5-Amino-1-[2-nitro-4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile; 5-Amino-1-(2-nitro-4-trifluoromethylphenyl)-1H-pyrazole-4-carbonitrile; 1H-Pyrazole-4-carbonitrile, 5-amino-1-[2-nitro-4-(trifluoromethyl)phenyl]-; 5-Amino-1-(2-nitro-α,α,α-trifluoro-p-tolyl)-1H-pyrazole-4-carbonitrile; 74990-43-5; 5-Amino-1-(2-nitro-4-trifluoromethylphenyl)pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-1-[2-Nitro-4-(Trifluoromethyl)Phenyl]-1H-Pyrazole-4-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.