Description

Ethanone, 1-(4-Ethenylphenyl)-2,2-Difluoro- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoroacetyl group attached to a vinylbenzene scaffold, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients. Its specific structure makes it a valuable precursor for creating complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, or binding affinity.
• Agrochemical Synthesis: Used in constructing advanced active ingredients for crop protection, where the fluorine atoms can improve pesticidal activity and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development, exploring new fluorination reactions, and creating complex molecular architectures.
• Fine Chemical Manufacturing: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for various technological applications.

Basic Information

Product Name	Ethanone, 1-(4-Ethenylphenyl)-2,2-Difluoro- (9Ci)
CAS No.	74946-48-8
Molecular Formula	C10H8F2O
Molecular Weight	182.17 g/mol
Synonyms	1-(4-Vinylphenyl)-2,2-difluoroethanone; 2,2-Difluoro-1-(4-vinylphenyl)ethanone; 4-Vinyl-α,α-difluoroacetophenone; p-Vinyl-α,α-difluoroacetophenone; Difluoro(4-vinylphenyl)methanone; (4-Ethenylphenyl)difluoromethyl ketone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production follows cGMP principles where applicable, and every batch is analyzed to ensure consistency and purity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as identity, assay, and impurity profiles. Our quality system is designed to meet the exacting standards of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.