Description

2-Amino-4-(4-Methoxy-Phenyl)-5,6,7,8-Tetrahydro-Quinoline-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for synthesizing novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex nitrogen-containing heterocycles for agrochemical and material science applications.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2-Amino-4-(4-Methoxy-Phenyl)-5,6,7,8-Tetrahydro-Quinoline-3-Carbonitrile
CAS No.	74873-46-4
Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34 g/mol
Synonyms	2-Amino-4-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 4-(4-Methoxyphenyl)-2-amino-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 74873-46-4; 2-Amino-4-(p-methoxyphenyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile; Tetrahydroquinoline-3-carbonitrile derivative; AQTC Intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(4-Methoxy-Phenyl)-5,6,7,8-Tetrahydro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.