Description

2,2'-Dibromo-1,1'-Binaphthyl CAS NO 74866-28-7 is a halogenated binaphthyl derivative, a versatile chiral building block and ligand precursor in advanced organic synthesis. Its value lies in its rigid, atropisomeric structure, which is crucial for inducing stereoselectivity in catalytic reactions and constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly for developing novel catalysts and functional organic compounds.

Application

• Chiral Ligand Synthesis: A key precursor for synthesizing axially chiral phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Serves as a critical building block in the research and development of chiral active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in creating stereoselective herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of chiral organic semiconductors, liquid crystals, and polymers with specific optical properties.
• Asymmetric Catalysis Research: Fundamental for academic and industrial R&D in developing new enantioselective synthetic methodologies.
• Cross-Coupling Reactions: Acts as a substrate or intermediate in Suzuki, Negishi, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	2,2'-Dibromo-1,1'-Binaphthyl
CAS No.	74866-28-7
Molecular Formula	C₂₀H₁₂Br₂
Molecular Weight	412.12 g/mol
Synonyms	2,2'-Dibromobinaphthyl; 2,2'-Dibromo-1,1'-binaphthalene; 1,1'-Binaphthalene, 2,2'-dibromo-; BINOL, 2,2'-dibromo-; 2,2'-Dibromo-[1,1'-binaphthalene]-4,4'-diol (precursor form); DBBN
EINECS	Contact for details

Quality Control

Our 2,2'-Dibromo-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.