Description

13(S)-Hotre is a high-purity, stereospecific chemical intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a valuable chiral building block for the production of complex bioactive molecules. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and fine chemical industries seeking to create enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandins, leukotrienes, and other bioactive lipid mediators.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other specialty chemicals requiring precise stereocontrol.
• Biochemical Research: Employed in studies of enzyme mechanisms, signal transduction pathways, and lipid metabolism.
• Material Science: Investigated as a building block for novel polymers and liquid crystals with unique optical properties.
• Academic & Contract Research: A critical reagent for methodological development in asymmetric synthesis and total synthesis projects.

Basic Information

Product Name	13(S)-Hotre
CAS No.	74784-20-6
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	13(S)-Hydroxy-9Z,11E-octadecadienoic acid; 13(S)-HODE; (13S)-Hydroxyoctadeca-9Z,11E-dienoic acid; 13(S)-HOTrE; 13S-HOTRE; Linoleic acid, 13-hydroxy-, (13S)-; 13S-Hydroxy-9Z,11E-octadecadienoic acid
EINECS	Contact for details

Quality Control

Every batch of 13(S)-Hotre is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for chiral purity, chemical assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). Allow the product to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (13S)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.