Description

n-Lauroyl-D-Erythro-Sphingosine is a synthetic, high-purity sphingolipid derivative, specifically an N-acylated sphingosine. This compound serves as a critical biochemical tool and a key intermediate in lipid metabolism research and advanced pharmaceutical development. It is essential for researchers and manufacturers in the life sciences, particularly those focused on cell signaling, membrane biophysics, and the synthesis of complex bioactive lipids. Its defined structure provides a reliable standard for studying ceramide-related pathways and developing novel therapeutic agents.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in mass spectrometry and chromatography for lipidomics studies.
• Cell Biology & Signaling: Investigates the role of specific ceramide species in apoptosis, cell differentiation, and stress responses.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex sphingolipid-based drug candidates and prodrugs.
• Lipid Membrane Studies: Employed in model membrane systems (e.g., liposomes) to study lipid-protein interactions and membrane permeability.
• Cosmeceutical Research: Explored for its potential bioactivity in skin barrier function and as a precursor for skin-identical lipids in advanced formulations.
• Enzyme Substrate: Acts as a specific substrate for enzymes like ceramidases and sphingomyelin synthases in enzymatic assays.

Basic Information

Product Name	n-Lauroyl-D-Erythro-Sphingosine
CAS No.	74713-60-3
Molecular Formula	C30H59NO3
Molecular Weight	481.80 g/mol
Synonyms	N-Lauroyl-D-erythro-sphingosine; D-erythro-N-Lauroylsphingosine; Lauroyl Ceramide (d18:1/12:0); (2S,3R,4E)-2-Dodecanoylamino-4-octadecene-1,3-diol; C12-Ceramide (d18:1/12:0); N-(Dodecanoyl)-D-erythro-sphingosine; N-Lauroylsphingosine; Sphingosine, N-lauroyl-D-erythro-
EINECS	Contact for details

Quality Control

Our n-Lauroyl-D-Erythro-Sphingosine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, ethanol, chloroform; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.