Description

1-(3-Bromophenoxy)-2-Fluoro-4-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining bromo, fluoro, and nitro substituents on a biphenyl ether scaffold, which enables precise structural modifications in target molecules. It is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing complex aromatic ether cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the halogen and nitro groups impart specific biological activity.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Nucleophilic Aromatic Substitution: The activated fluoro and nitro groups allow for selective displacement reactions to introduce diverse functionalities.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-(3-Bromophenoxy)-2-Fluoro-4-Nitrobenzene
CAS No.	74660-86-9
Molecular Formula	C12H7BrFNO3
Molecular Weight	312.10 g/mol
Synonyms	2-Fluoro-4-nitro-1-(3-bromophenoxy)benzene; 1-Bromo-3-[(2-fluoro-4-nitrophenyl)oxy]benzene; 3-Bromophenyl 2-fluoro-4-nitrophenyl ether; 2-Fluoro-4-nitrophenyl 3-bromophenyl ether; 1-(3-Bromophenoxy)-2-fluoro-4-nitro-benzene
EINECS	Contact for details

Quality Control

Our 1-(3-Bromophenoxy)-2-Fluoro-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.