Description

9,10-Dihydrobenzo(E)Pyrene-9,10-Diol trans-(+-)- is a high-purity, stereospecific dihydrodiol derivative of benzo[e]pyrene, a polycyclic aromatic hydrocarbon (PAH). This compound is of significant value as a critical reference standard and metabolic intermediate in advanced chemical and biological research. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and academic research institutions for studies involving PAH metabolism, carcinogenicity, and environmental toxicology.

Application

• Metabolic and Toxicological Research: Serves as a key intermediate or reference standard in studying the metabolic activation pathways of benzo[e]pyrene and related PAHs.
• Analytical Chemistry: Used as a certified reference material (CRM) for the calibration of analytical instruments like HPLC, GC-MS, and LC-MS in environmental and biological monitoring.
• Biomarker Development: Employed in the synthesis and study of DNA adducts for understanding mechanisms of chemical carcinogenesis and developing exposure biomarkers.
• Pharmaceutical Screening: Acts as a reagent or standard in assays designed to evaluate the efficacy of chemopreventive agents against PAH-induced toxicity.
• Environmental Science: Utilized in research focused on the biodegradation, bioactivation, and environmental fate of complex polycyclic aromatic compounds.
• Academic Synthesis Studies: Provides a defined stereochemical starting point or target molecule for advanced organic synthesis and methodology development.

Basic Information

Product Name	9,10-Dihydrobenzo(E)Pyrene-9,10-Diol trans-(+-)-
CAS No.	74634-55-2
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.33 g/mol
Synonyms	trans-(±)-9,10-Dihydroxy-9,10-dihydrobenzo[e]pyrene; Benzo[e]pyrene-9,10-dihydrodiol (trans, racemic); (±)-trans-9,10-Dihydrobenzo[e]pyrene-9,10-diol; B[e]P-9,10-diol; 9,10-Dihydroxybenzo[e]pyrene-9,10-dihydro; trans-(±)-BP-9,10-dihydrodiol; Benzo(e)pyrene dihydrodiol; 9,10-Dihydro-9,10-dihydroxybenzo[e]pyrene
EINECS	Contact for details

Quality Control

Our 9,10-Dihydrobenzo(E)Pyrene-9,10-Diol trans-(+-)- is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques, and a comprehensive Certificate of Analysis (COA) detailing identity, purity, and chromatographic data is provided. We adhere to ISO-guided quality management principles to support the integrity of your scientific work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect the compound from moisture and atmospheric oxidation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.