Description

3-Iodo-4-Methoxyaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a methoxy group on the aromatic ring, makes it a valuable intermediate for constructing complex molecules with specific electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators that require halogenated aniline cores.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and organic pigments, where the iodine atom contributes to color fastness and specific hue properties.
• Material Science Research: Intermediate in the creation of organic semiconductors, liquid crystals, and photoactive polymers for electronic applications.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck, Sonogashira) due to the reactive iodine moiety, enabling carbon-carbon bond formation.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in both academic and industrial R&D settings for exploring new synthetic pathways.

Basic Information

Product Name	3-Iodo-4-Methoxyaniline
CAS No.	74587-12-5
Molecular Formula	C7H8INO
Molecular Weight	249.05 g/mol
Synonyms	4-Amino-2-iodoanisole; 2-Iodo-4-methoxyaniline; 4-Methoxy-3-iodoaniline; 3-Iodo-p-anisidine; 3-Iodo-4-methoxybenzenamine; 2-Iodo-4-aminoanisole; Benzenamine, 3-iodo-4-methoxy-
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-Methoxyaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global B2B clients in fine chemical sectors. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.