Description

Calix[4]arene is a versatile macrocyclic organic compound belonging to the calixarene family, characterized by a cup-shaped molecular structure formed from phenolic units. This unique three-dimensional architecture makes it an exceptional host molecule in supramolecular chemistry for selectively binding ions and neutral molecules. It is a critical building block and research chemical for scientists and engineers in advanced material science, pharmaceutical development, and environmental technology sectors seeking to develop novel sensors, catalysts, and separation agents.

Application

• Supramolecular Chemistry & Host-Guest Systems: Acts as a molecular scaffold or receptor for cations, anions, and neutral organic molecules.
• Chemical Sensors & Detection: Used as an active sensing layer in electrodes and optical sensors for the selective detection of specific ions or pollutants.
• Catalysis & Organic Synthesis: Serves as a ligand to stabilize metal catalysts or as a nanoreactor due to its defined cavity, enhancing reaction selectivity and efficiency.
• Separation Science & Extraction: Employed in the development of stationary phases for chromatography or as extractants in liquid-liquid extraction processes for metal ions and organic compounds.
• Nanotechnology & Material Science: A foundational unit for constructing molecular machines, self-assembled monolayers, and advanced porous materials like metal-organic frameworks (MOFs).
• Pharmaceutical Research: Investigated for drug delivery applications, utilizing its cavity to encapsulate and transport active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Calix[4]arene
CAS No.	74568-07-3
Molecular Formula	C28H24O4
Molecular Weight	424.49 g/mol
Synonyms	p-tert-Butylcalix[4]arene; 5,11,17,23-Tetra-tert-butyl-25,26,27,28-tetrahydroxycalix[4]arene; Calix-4-arene; 1,3,5,7(1,3)-Tetrabenzenacyclooctaphane-24,25,26,27-tetrol; Tetrameric p-tert-butylphenol-formaldehyde condensate; BC4; CA[4]
EINECS	Contact for details

Quality Control

Our Calix[4]arene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and melting point determination, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	342 - 346 °C
Loss on Drying	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.