Description

2,2',3,4',5,6,6'-Heptachlorobiphenyl CAS NO 74487-85-7 is a specific, highly chlorinated congener of the polychlorinated biphenyl (PCB) family, characterized by its seven chlorine atoms arranged in a defined substitution pattern. This compound is of significant importance as a high-purity analytical reference standard and a critical material for environmental and toxicological research. It is primarily required by analytical laboratories, research institutions, and regulatory bodies engaged in the identification, quantification, and study of PCB contamination and its biological impacts.

Application

• Environmental Analysis Reference Standard: Primary use as a certified reference material (CRM) for the calibration and validation of analytical methods (GC-MS, GC-ECD) in testing soil, water, sediment, and biota samples.
• Toxicological and Biomedical Research: Serves as a key congener in studies investigating the metabolism, pharmacokinetics, and specific toxic effects (e.g., endocrine disruption, carcinogenicity) of PCBs.
• Method Development and Proficiency Testing: Essential for developing new analytical protocols and as a component in inter-laboratory comparison programs to ensure data accuracy and consistency across testing facilities.
• Regulatory Compliance and Monitoring: Used to support compliance testing against international regulations (e.g., Stockholm Convention, EPA methods) concerning persistent organic pollutants (POPs).
• Forensic Source Identification: Aids in chemical fingerprinting to trace the source and history of PCB contamination in environmental forensic investigations.
• Quality Control Material Production: Employed by manufacturers to produce in-house quality control materials and spiked samples for internal laboratory quality assurance.

Basic Information

Product Name	2,2',3,4',5,6,6'-Heptachlorobiphenyl
CAS No.	74487-85-7
Molecular Formula	C₁₂H₃Cl₇
Molecular Weight	395.32 g/mol
Synonyms	PCB 183; 2,2',3,4',5,6,6'-Heptachloro-1,1'-biphenyl; 1,1'-Biphenyl, 2,2',3,4',5,6,6'-heptachloro-; Heptachlorobiphenyl (PCB 183); BZ# 183; Congener 183; 2,2',3,4',5,6,6'-Heptachlorodiphenyl
EINECS	Contact for details

Quality Control

Every batch of our 2,2',3,4',5,6,6'-Heptachlorobiphenyl is produced and verified under strict quality management protocols to ensure the identity, purity, and stability required for high-end analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing lot-specific results from advanced chromatographic and spectroscopic techniques. Our quality systems support compliance with relevant standards for reference materials, and we offer materials traceable to NIST or other recognized certifying bodies upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as indicated on the product label or Certificate of Analysis. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (GC)	Conforms to reference retention time
Purity (GC-FID/GC-MS)	≥ 98.0% (area percent)
Related Substances (GC)	Total other PCBs ≤ 1.5%
Solubility	Soluble in common organic solvents (e.g., hexane, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.