Description

Diethyl 2-(4-Chlorophenyl)-1,1-Cyclopropanedicarboxylate is a high-purity, synthetically valuable cyclopropane derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique sterically constrained structure makes it an essential building block for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the cyclopropane ring contributes to biological activity and stability.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Organic Synthesis Building Block: Facilitates complex transformations such as ring-opening reactions, cross-coupling, and chiral synthesis in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Diethyl 2-(4-Chlorophenyl)-1,1-Cyclopropanedicarboxylate
CAS No.	74444-83-0
Molecular Formula	C15H17ClO4
Molecular Weight	296.75 g/mol
Synonyms	1,1-Cyclopropanedicarboxylic acid, 2-(4-chlorophenyl)-, diethyl ester; Diethyl 2-(p-chlorophenyl)-1,1-cyclopropanedicarboxylate; Ethyl 2-(4-chlorophenyl)-1,1-cyclopropanedicarboxylate; 2-(4-Chlorophenyl)-1,1-cyclopropanedicarboxylic acid diethyl ester; (4-Chlorophenyl)cyclopropane-1,1-dicarboxylic acid diethyl ester; Diethyl (4-chlorophenyl)cyclopropane-1,1-dicarboxylate
EINECS	Contact for details

Quality Control

Every batch of Diethyl 2-(4-Chlorophenyl)-1,1-Cyclopropanedicarboxylate is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets a typical purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.