Description

3-Iodo-5-Methoxybenzoic Acid is a versatile iodinated aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a methoxy group on the benzoic acid core, makes it a valuable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating libraries of bioactive compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where its halogenated structure is advantageous.
• Ligand and Catalyst Synthesis: Serves as a starting material for preparing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Building block for synthesizing advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological systems due to the reactivity of the iodine atom.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	3-Iodo-5-Methoxybenzoic Acid
CAS No.	74440-82-7
Molecular Formula	C8H7IO3
Molecular Weight	278.05 g/mol
Synonyms	5-Methoxy-3-iodobenzoic Acid; 3-Iodo-5-methoxybenzoic acid; Benzoic acid, 3-iodo-5-methoxy-; 3-Iodo-5-anisic acid; 74440-82-7; 3-I-5-MeO-BA
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methoxybenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.