Description

Man(5)GlcNAc(4)Asn is a complex, high-purity asparagine-linked oligosaccharide, a key structural component of N-linked glycoproteins. This compound is essential for researchers and manufacturers in the biopharmaceutical industry, serving as a critical reference standard and intermediate for glycan analysis and synthesis. It is primarily utilized by professionals in glycobiology research, therapeutic protein characterization, and the development of biosimilars and novel biologics.

Application

• Glycobiology Research Standard: Used as a high-purity reference compound for studying N-glycan biosynthesis, processing, and function.
• Therapeutic Protein Characterization: Acts as a critical standard in analytical methods like HPLC and MS for profiling the glycosylation patterns of monoclonal antibodies and other biologics.
• Enzyme Substrate/Inhibitor Studies: Employed in assays to investigate the activity and specificity of glycosidases and glycosyltransferases.
• Biosimilar Development: Supports comparability studies by providing a defined glycan standard to ensure product consistency and quality.
• Glycan Array Fabrication: Can be used in the synthesis of glycan arrays for high-throughput analysis of protein-glycan interactions.
• Cell Culture Media Supplement: Investigated for its potential role in modulating glycosylation profiles in cell culture systems for bioproduction.

Basic Information

Product Name	Man(5)GlcNAc(4)Asn
CAS No.	74424-56-9
Molecular Formula	C44H75N3O36
Molecular Weight	1198.06 g/mol
Synonyms	M5N2; High-Mannose Type Oligosaccharide M5N2; Man5GlcNAc2-Asn; N-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R,4R,5R)-5-[[(2R,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxyoxolan-2-yl]methoxy]-4-carbamoylbutanoyl]amino]-3-carbamoylpropanoic Acid
EINECS	Contact for details

Quality Control

Every batch of Man(5)GlcNAc(4)Asn is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous purity and identity testing using advanced analytical techniques including HPLC and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.