Description

4-Iodoaniline Hydrochloride is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in the iodine substituent, which provides a reactive handle for cross-coupling reactions and further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring iodine for radio-labeling or structural diversity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodoaniline moiety is incorporated into the final product structure.
• Material Science Research: Building block for creating organic electronic materials, liquid crystals, and advanced polymers with specific optoelectronic properties.
• Cross-Coupling Reactions: Essential substrate in palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to form complex biaryl and conjugated systems.
• Dye and Pigment Manufacturing: Intermediate in the production of specialized dyes and pigments, leveraging the aniline structure for color development.
• Chemical Research & Development: Serves as a standard reagent and starting material in academic and industrial R&D labs for method development and novel compound libraries.

Basic Information

Product Name	4-Iodoaniline Hydrochloride
CAS No.	74367-81-0
Molecular Formula	C6H7ClIN
Molecular Weight	255.49 g/mol
Synonyms	p-Iodoaniline Hydrochloride; 4-Iodoaniline HCl; 1-Amino-4-iodobenzene Hydrochloride; Benzenamine, 4-iodo-, hydrochloride; 4-Iodophenylamine Hydrochloride; p-Iodophenylamine Hydrochloride; (4-Iodophenyl)ammonium chloride
EINECS	Contact for details

Quality Control

Our 4-Iodoaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.