Description

(4R,5S)-4-Acetoxy-4,4Aα,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-8,8-Dimethylspiro[5H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-5,2'-Oxirane]-1-Methanol is a high-purity, complex spirocyclic and polycyclic organic compound featuring a unique molecular architecture. This compound is valued as a critical chiral intermediate and building block in advanced organic synthesis, enabling the construction of sophisticated molecular frameworks. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for complex small-molecule drugs.
• Agrochemical Synthesis: Used as a building block in the creation of advanced pesticides and herbicides with specific stereochemical requirements.
• Organic Synthesis Research: A valuable reagent for methodological studies in asymmetric synthesis, cycloaddition reactions, and the construction of complex polycyclic systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials where precise stereochemistry is essential.
• Academic & Industrial R&D: Supports chemical biology and medicinal chemistry programs in universities and corporate R&D laboratories.

Basic Information

Product Name	(4R,5S)-4-Acetoxy-4,4Aα,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-8,8-Dimethylspiro[5H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-5,2'-Oxirane]-1-Methanol
CAS No.	74320-18-6
Molecular Formula	C17H24O5
Molecular Weight	308.37 g/mol
Synonyms	4-Acetoxy-4,4a,6,7,7a,8,8a,8b-octahydro-8,8-dimethylspiro[5H-cyclopropa[3,4]cyclohepta[1,2-c]pyran-5,2'-oxirane]-1-methanol; (4R,5S)-rel-4-(Acetyloxy)-4,4a,6,7,7a,8,8a,8b-octahydro-8,8-dimethylspiro[5H-cyclopropa[3,4]cyclohepta[1,2-c]pyran-5,2'-oxirane]-1-methanol; Spiro[5H-cyclopropa[3,4]cyclohepta[1,2-c]pyran-5,2'-oxirane]-1-methanol derivative; CAS 74320-18-6
EINECS	Contact for details

Quality Control

Our production of (4R,5S)-4-Acetoxy-4,4Aα,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-8,8-Dimethylspiro[5H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-5,2'-Oxirane]-1-Methanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.