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(R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl CAS NO 74292-20-9


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CAS No.:74292-20-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is a high-value, enantiomerically pure chiral ligand and building block essential for asymmetric synthesis. Its core value lies in its ability to induce high stereoselectivity in catalytic reactions, which is critical for producing single-enantiomer pharmaceuticals and fine chemicals. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel chiral compounds.

Application

  • Asymmetric Catalysis: As a chiral ligand for transition metal catalysts (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and other key transformations.
  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and complex drug candidates.
  • Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
  • Material Science: A building block for chiral polymers, liquid crystals, and other functional materials with optical properties.
  • Academic & Industrial Research: A standard reagent for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name (R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl
CAS No. 74292-20-9
Molecular Formula C26H24O4
Molecular Weight 400.47 g/mol
Synonyms (R)-(+)-BINOL-DMOM; (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl; (R)-DMOM-BINOL; (R)-(+)-1,1'-Bi-2-naphthol Dimethyl Ether Derivative; (R)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-binaphthyl-2,2'-diyl Dimethyl Ether (incorrect but common misnomer); (R)-2,2'-Di(methoxymethoxy)-1,1'-binaphthyl; (R)-BINOL bis(methyl ether) protected derivative
EINECS Contact for details

Quality Control

Our (R)-(+)-2,2'-Bis(Methoxymethoxy)-1,1'-Binaphthyl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess (ee), and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Enantiomeric Excess (ee) ≥ 99.0%
Melting Point Contact for details
Specific Rotation Contact for details
Heavy Metals < 10 ppm
Residual Solvents Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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