Description

(4Ar,5R,6S)-5-[(S)-2-Chloro-1-Hydroxyethyl]-6-(β-D-Glucopyranosyloxy)-4,4A,5,6-Tetrahydro-4A-Hydroxy-1H,3H-Pyrano[3,4-C]Pyran-1-One is a complex, high-purity chiral compound with a defined stereochemistry and a glucopyranosyl moiety. This molecule is of significant interest for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists working in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas like antibiotic development and glycosidase inhibitor research.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of complex drug candidates, especially novel antibiotics and enzyme inhibitors.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis (HPLC, LC-MS).
• Biochemical Research: Employed in enzymatic and biological studies to investigate glycosylation processes and carbohydrate-protein interactions.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing reaction conditions in pilot plants and kilo-labs.
• Academic Research: A valuable compound for universities and research institutes studying organic synthesis, medicinal chemistry, and natural product derivatives.

Basic Information

Product Name	(4Ar,5R,6S)-5-[(S)-2-Chloro-1-Hydroxyethyl]-6-(β-D-Glucopyranosyloxy)-4,4A,5,6-Tetrahydro-4A-Hydroxy-1H,3H-Pyrano[3,4-C]Pyran-1-One
CAS No.	74213-76-6
Molecular Formula	C₁₆H₂₁ClO₁₀
Molecular Weight	408.78 g/mol
Synonyms	5-[(1S)-2-Chloro-1-hydroxyethyl]-6-(β-D-glucopyranosyloxy)-4a,5,6,7-tetrahydro-4a-hydroxy-1H,3H-pyrano[3,4-c]pyran-1-one; (4aR,5R,6S,7S)-5-[(1S)-2-Chloro-1-hydroxyethyl]-6-(β-D-glucopyranosyloxy)-4a,5,6,7-tetrahydro-4a-hydroxy-1H,3H-pyrano[3,4-c]pyran-1-one; Chlorinated glucosyl pyranopyranone derivative; CAS 74213-76-6
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a comprehensive quality management system. Certificates of Analysis (COA) providing detailed purity and identification data (typically by HPLC, NMR, and optical rotation) are available upon request. Specifications can be aligned with client requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.