Description

(17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolane]-4,9,11-Triene 2'-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex steroidal spiro-oxathiolane structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting hormone-related pathways. It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic candidates with modified biological activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating steroid receptor interactions and metabolic pathways.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes for complex steroidal molecules.

Basic Information

Product Name	(17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolane]-4,9,11-Triene 2'-Oxide
CAS No.	74183-66-7
Molecular Formula	C19H24O3S
Molecular Weight	332.46 g/mol
Synonyms	3-Oxo-17-spiro(19-norandrost-4,9,11-triene-17,5'-[1,2]oxathiolane) 2'-oxide; 19-Norandrosta-4,9,11-triene-17-spiro-5'-[1,2]oxathiolane]-3-one 2'-oxide; (17R)-Spiro[19-norandrosta-4,9,11-triene-17,5'-[1,2]oxathiolane]-3-one 2'-oxide; Steroidal spiro-oxathiolane derivative; 74183-66-7; 19-Norandrostane spiro-oxathiolane oxide.
EINECS	Contact for details

Quality Control

Our (17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolane]-4,9,11-Triene 2'-Oxide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.