Description

(17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolan]-4-Ene 2'-Oxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex steroidal spiro-oxathiolane structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting hormone-related pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel steroidal drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic candidates.
• Hormone Analog Development: Serves as a precursor in the development of modified hormone analogs with potential therapeutic applications.
• Academic & Institutional Research: Employed in university and institutional labs for advanced organic synthesis and chemical methodology studies.
• Process Chemistry: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs) during process development.
• Reference Standard: Can serve as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolan]-4-Ene 2'-Oxide
CAS No.	74183-64-5
Molecular Formula	C19H26O3S
Molecular Weight	334.48 g/mol
Synonyms	(17R)-3-Oxospiro[19-norandrost-4-ene-17,5'-[1,2]oxathiolane] 2'-Oxide; 19-Norandrost-4-ene-3,17-dione, cyclic 17-(1,2-oxathiolane) S-oxide, (17R)-; Spiro[19-norandrost-4-ene-17,5'-[1,2]oxathiolane]-3-one 2'-oxide, (17R)-; CAS 74183-64-5; Steroidal Spiro-oxathiolane Oxide; 19-Nor Steroid Intermediate
EINECS	Contact for details

Quality Control

Our (17R)-3-Oxospiro[19-Norandrostane-17,5'-[1,2]Oxathiolan]-4-Ene 2'-Oxide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.