Description

4-Bromopyridine Hydrobromide is a versatile and highly reactive halogenated pyridine derivative, essential as a key building block in advanced organic synthesis. Its primary value lies in its dual functionality, offering both a bromine atom for cross-coupling reactions and a pyridine nitrogen for coordination or further functionalization. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromopyridine moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings to form biaryl and heterobiaryl structures.
• Nucleophilic Substitution: The bromine atom can be readily displaced by various nucleophiles to introduce diverse functional groups onto the pyridine ring.

Basic Information

Product Name	4-Bromopyridine Hydrobromide
CAS No.	74129-11-6
Molecular Formula	C5H5BrN·HBr
Molecular Weight	258.92 g/mol
Synonyms	4-Bromopyridine HBr Salt; Pyridine, 4-bromo-, hydrobromide (1:1); 4-Bromopyridine Hydrobromide Salt; 4-BrPy·HBr; 4-Bromopyridinium Bromide; 4-BP·HBr; 4-Bromopyridine Monohydrobromide
EINECS	Contact for details

Quality Control

Our 4-Bromopyridine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0 - 103.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.