Description

α-Methyl-4α-Phenylcyclohexane-1β-Ethanamine is a specialized organic amine compound featuring a unique cyclohexane-phenyl backbone. This structural motif makes it a valuable chiral intermediate and building block in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecules. Its specific stereochemistry is critical for applications requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the research and synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers with high enantioselectivity.
• Fine Chemical Production: Serves as a specialized intermediate in the manufacture of complex agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Employed in methodological studies and process chemistry development for new synthetic routes.
• Ligand and Catalyst Development: Potential use in the design of novel chiral ligands for transition metal catalysis.

Basic Information

Product Name	α-Methyl-4α-Phenylcyclohexane-1β-Ethanamine
CAS No.	74068-04-5
Molecular Formula	C15H23N
Molecular Weight	217.35 g/mol
Synonyms	1β-(2-Aminoethyl)-α-methyl-4α-phenylcyclohexane; (1R,4R)-1-(2-Aminoethyl)-4-methyl-4-phenylcyclohexane; α-Methyl-4α-phenylcyclohexaneethanamine; 74068-04-5; 4α-Phenyl-α-methylcyclohexaneethanamine; (1β,4α)-1-(2-Aminoethyl)-4-methyl-4-phenylcyclohexane
EINECS	Contact for details

Quality Control

Our α-Methyl-4α-Phenylcyclohexane-1β-Ethanamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.