Description

3,5-Diiodo-L-Tyrosine Ethyl Ester Hydrochloride is a halogenated tyrosine derivative, a key iodinated building block in organic synthesis and pharmaceutical research. This compound is valued for its role as a versatile intermediate in the development of thyroid hormone analogs, radiopharmaceuticals, and other bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of thyroid hormone analogs and related therapeutic agents.
• Radiopharmaceutical Precursor: Used in research for developing iodine-123 or iodine-131 labeled compounds for diagnostic imaging and therapy.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to tyrosine metabolism and iodination pathways.
• Peptide Synthesis: Incorporated into peptide chains to study structure-activity relationships or to create novel bioactive peptides.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis: A versatile intermediate for further chemical modifications, enabling the creation of complex, iodinated organic molecules.

Basic Information

Product Name	3,5-Diiodo-L-Tyrosine Ethyl Ester Hydrochloride
CAS No.	74051-47-1
Molecular Formula	C11H13I2NO3 • HCl
Molecular Weight	514.49 g/mol
Synonyms	L-Tyrosine, 3,5-diiodo-, ethyl ester, hydrochloride; Ethyl 3,5-diiodo-L-tyrosinate hydrochloride; 3,5-Diiodotyrosine ethyl ester HCl; DIH HCl; (2S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid ethyl ester hydrochloride; 3,5-Diiodo-L-tyrosine ethyl ester monohydrochloride; 3,5-Diiodo-O-ethyl-L-tyrosine hydrochloride
EINECS	Contact for details

Quality Control

Our 3,5-Diiodo-L-Tyrosine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for residual solvents and heavy metals, ensuring it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.