Description

1-Hydroxy-2-Methylpropylphosphonic Acid Diethyl Ester is a specialized organophosphorus compound that serves as a versatile intermediate in advanced chemical synthesis. Its unique structure, featuring both phosphonic ester and hydroxyl functionalities, makes it a valuable building block for creating complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality precursors for their development and production processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting bone-related disorders or requiring phosphonate moieties.
• Agrochemical Synthesis: Used as a precursor for developing advanced herbicides, plant growth regulators, and fungicides with enhanced efficacy and environmental profiles.
• Ligand and Chelating Agent Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis, metal extraction, and water treatment processes.
• Flame Retardant Additive Development: Incorporated into research for creating new generation, halogen-free flame retardants for polymers and textiles.
• Material Science Research: Employed in the development of functionalized surfaces, metal-organic frameworks (MOFs), and other advanced materials.
• Chemical Synthesis Reagent: Acts as a phosphorylating agent or a protected phosphonic acid equivalent in multi-step organic syntheses.

Basic Information

Product Name	1-Hydroxy-2-Methylpropylphosphonic Acid Diethyl Ester
CAS No.	74038-47-4
Molecular Formula	C8H19O4P
Molecular Weight	210.21 g/mol
Synonyms	Diethyl (1-Hydroxy-2-Methylpropyl)phosphonate; (1-Hydroxy-2-Methylpropyl)phosphonic Acid Diethyl Ester; 2-Methyl-1-(diethoxyphosphinyl)-1-propanol; Phosphonic acid, P-(1-hydroxy-2-methylpropyl)-, diethyl ester; Isobutylhydroxyphosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-2-Methylpropylphosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Gravity (20°C)	1.080 - 1.120
Refractive Index (20°C)	1.430 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.