Description

4-Chloro-3-Methoxytoluene is a versatile chlorinated aromatic ether compound, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen site and a methoxy directing group, enabling precise chemical modifications for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted toluene backbone.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and pesticides, leveraging its halogen and ether functionalities.
• Dye and Pigment Production: Serves as an intermediate for synthesizing complex organic dyes and colorants.
• Liquid Crystal Materials: A potential building block for the synthesis of organic compounds used in electronic display technologies.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Flavor and Fragrance Industry: Intermediate for the production of certain aromatic chemicals.

Basic Information

Product Name	4-Chloro-3-Methoxytoluene
CAS No.	73909-16-7
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	1-Chloro-4-methoxy-2-methylbenzene; 2-Methyl-4-chloroanisole; 4-Chloro-3-methylanisole; 3-Methoxy-4-chlorotoluene; p-Chloro-m-methoxytoluene; 4-Chloro-3-methoxy-1-methylbenzene; Toluene, 4-chloro-3-methoxy-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Methoxytoluene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request, supporting compliance in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.