Description

Benzeneacetic Acid, -α--Ethyl-4-Methyl-, (-α-S)- (9Ci) CAS NO 73853-94-8 is a chiral, non-racemic organic compound belonging to the class of substituted phenylacetic acid derivatives. This specific stereoisomer is of significant value for its role as a key chiral intermediate or building block in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries. The compound's defined stereochemistry enables the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Synthesis: Used as a starting material or resolving agent in stereoselective synthesis to construct complex molecules with high optical purity.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, including advanced ligands for catalysis and chiral auxiliaries.
• Agrochemical Research: Employed in the development of novel, chiral agrochemicals such as herbicides and pesticides where specific stereochemistry impacts biological activity.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development in organic chemistry and for studying structure-activity relationships (SAR).
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing chiral aroma chemicals and fragrance ingredients with specific olfactory properties.

Basic Information

Product Name	Benzeneacetic Acid, -α--Ethyl-4-Methyl-, (-α-S)- (9Ci)
CAS No.	73853-94-8
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(S)-2-Ethyl-2-(4-methylphenyl)acetic acid; (S)-α-Ethyl-4-methylbenzeneacetic acid; (S)-2-(4-Methylphenyl)butanoic acid; (-)-(S)-2-Ethyl-2-(p-tolyl)acetic acid; (S)-p-Methyl-α-ethylphenylacetic acid; L-73853; (S)-2-(4-Methylphenyl)butyric acid; (αS)-α-Ethyl-4-methylbenzenecetic acid
EINECS	Contact for details

Quality Control

Our production of Benzeneacetic Acid, -α--Ethyl-4-Methyl-, (-α-S)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet exacting standards. Certificates of Analysis (COA) detailing specifications such as assay, chiral purity (by HPLC), and impurity profiles are provided and available upon request. Our quality systems support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.