Description

8-(4-Ethoxy-3-Methoxyphenyl)-1,5-Diazabicyclo[3.2.1]Octane is a high-purity, advanced pharmaceutical intermediate characterized by its unique diazabicyclooctane core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D laboratories, custom synthesis providers, and manufacturers in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its rigid bicyclic scaffold and functionalized aromatic ring.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with specific mode-of-action profiles.
• Ligand and Catalyst Development: The diazabicyclic nitrogen atoms can act as chelating sites for metal catalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.
• Academic and Industrial R&D: Employed in exploratory chemistry for developing new chemical entities and probing new synthetic methodologies.

Basic Information

Product Name	8-(4-Ethoxy-3-Methoxyphenyl)-1,5-Diazabicyclo[3.2.1]Octane
CAS No.	73825-80-6
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	8-(4-Ethoxy-3-methoxyphenyl)-1,5-diazabicyclo[3.2.1]octane; 1,5-Diazabicyclo[3.2.1]octane, 8-(4-ethoxy-3-methoxyphenyl)-; 8-(4-Ethoxy-3-methoxyphenyl)-1,5-diazabicyclo[3.2.1]octane; 73825-80-6; 8-(4-Ethoxy-3-methoxyphenyl)-1,5-diazabicyclo[3.2.1]octane (CAS 73825-80-6); 8-(4-Ethoxy-3-methoxyphenyl)-1,5-diazabicyclooctane
EINECS	Contact for details

Quality Control

Our 8-(4-Ethoxy-3-Methoxyphenyl)-1,5-Diazabicyclo[3.2.1]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.