Description

3-(5-Fluoro-2,4-Dinitroanilino)-Proxyl is a specialized nitroxide radical spin label, a key tool in electron paramagnetic resonance (EPR) spectroscopy and spin labeling studies. This compound is valued for its stability and specific reactivity, enabling researchers to probe molecular structure, dynamics, and interactions in complex biological and chemical systems. It is primarily required by R&D laboratories and analytical service providers in the pharmaceutical, biophysics, and materials science sectors for advanced research applications.

Application

• Spin Labeling in EPR Spectroscopy: Used as a covalent tag to study protein conformation, folding, and membrane protein dynamics.
• Biophysical Research: Employed to investigate nucleic acid structure, lipid bilayer properties, and polymer chain mobility.
• Structural Biology: Aids in determining distances within biomolecules through site-directed spin labeling (SDSL) techniques.
• Oxidative Stress Studies: Acts as a stable radical probe in models studying free radical reactions and antioxidant mechanisms.
• Polymer Science: Utilized to analyze polymer morphology, cross-linking density, and degradation processes.
• Pharmaceutical R&D: Supports drug discovery by studying drug-target interactions and the behavior of drug delivery systems.

Basic Information

Product Name	3-(5-Fluoro-2,4-Dinitroanilino)-Proxyl
CAS No.	73784-45-9
Molecular Formula	C14H16FN4O5
Molecular Weight	339.30 g/mol
Synonyms	3-(5-Fluoro-2,4-dinitroanilino)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy; 3-(5-Fluoro-2,4-dinitrophenylamino)-PROXYL; 5-Fluoro-2,4-dinitroanilino-Proxyl; 3-(5-Fluoro-2,4-dinitroanilino)-2,2,5,5-tetramethylpyrrolidine-1-oxyl; 3-(5-Fluoro-2,4-dinitroanilino)-TEMPO derivative; 5-F-DNPA-Proxyl; Proxyl spin label derivative; Nitroxide radical label CAS 73784-45-9
EINECS	Contact for details

Quality Control

Our 3-(5-Fluoro-2,4-Dinitroanilino)-Proxyl is produced under strict quality protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, EPR, and NMR to confirm identity, purity, and radical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (EPR)	Characteristic triplet signal
Purity (HPLC)	≥ 97.0%
Assay (EPR)	≥ 95.0% radical content
Melting Point	Contact for details
Solubility	Soluble in common organic solvents (e.g., DMSO, ethanol, chloroform)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.