Description

3-Quinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo- is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals, where its unique heterocyclic structure enables complex molecular transformations. It is essential for R&D chemists and production teams in the pharmaceutical, agrochemical, and material science industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting neurological and anti-infective pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the quinoline scaffold for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for the synthesis of electron-transport or emissive layer materials in display technologies.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for catalytic systems used in asymmetric synthesis and cross-coupling reactions.
• Chemical Research & Development: A versatile building block for academic and industrial research into new heterocyclic compounds and their properties.
• Dye and Pigment Intermediate: Used in the synthesis of specialized quinoline-based dyes for analytical and industrial applications.

Basic Information

Item	Detail
Product Name	3-Quinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo-
CAS No.	73776-24-6
Molecular Formula	C₁₀H₇NO₄
Molecular Weight	205.17 g/mol
Synonyms	1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylic acid; 4-Hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid; 3-Carboxy-4-hydroxy-1,2-dihydro-2-oxoquinoline; 4-Hydroxy-2-oxo-1H-quinoline-3-carboxylic acid; 1H-2-Oxo-4-hydroxyquinoline-3-carboxylic acid; Quinoline-3-carboxylic acid, 1,2-dihydro-4-hydroxy-2-oxo-; 73776-24-6
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1,2-Dihydro-4-Hydroxy-2-Oxo- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.