Description

2-Chloroquinoline-3-Carboxamide is a versatile and high-value heterocyclic building block, primarily recognized for its role as a key intermediate in advanced organic synthesis. Its core value proposition lies in enabling the construction of complex molecular architectures, particularly within the pharmaceutical and agrochemical research sectors. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where its specific chlorinated quinoline scaffold offers unique reactivity and functionalization potential.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, including kinase inhibitors, antimicrobial agents, and other biologically active quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinoline core.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and photoactive materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and amide bond transformations.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex molecules for various high-value industrial applications.

Basic Information

Product Name	2-Chloroquinoline-3-Carboxamide
CAS No.	73776-21-3
Molecular Formula	C10H7ClN2O
Molecular Weight	206.63 g/mol
Synonyms	2-Chloro-3-quinolinecarboxamide; 2-Chloroquinoline-3-carboxylic acid amide; 3-Carbamoyl-2-chloroquinoline; 2-Chloro-3-carbamoylquinoline; Quinoline-3-carboxamide, 2-chloro-; 73776-21-3; 2-Chlor-chinolin-3-carbonsäureamid (German)
EINECS	Contact for details

Quality Control

Our 2-Chloroquinoline-3-Carboxamide is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, and is supplied with a corresponding Certificate of Analysis (COA). We are committed to meeting the stringent requirements of research and development, and specifications can be aligned with client needs for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.