Description

3-Oxo-3H-2,1-Benzoxiodolium Chloride is a specialized iodonium salt compound, recognized for its role as a versatile reagent in organic synthesis. Its primary value lies in its ability to act as a highly effective electrophilic iodinating agent and a precursor for hypervalent iodine reagents, enabling key transformations in complex molecule construction. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for innovative synthetic routes.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent for the electrophilic introduction of iodine atoms into aromatic and heteroaromatic systems, a crucial step in developing active pharmaceutical ingredients (APIs).
• Hypervalent Iodine Reagent Precursor: Serves as a fundamental building block for generating various hypervalent iodine(III) reagents, such as (diffluoroiodo)arenes, used in fluorination and other oxidative functionalization reactions.
• Agrochemical Research & Development: Employed in the synthesis of novel iodinated compounds with potential biological activity for crop protection and pest management.
• Material Science & Polymer Chemistry: Facilitates the synthesis of iodonium-based photoinitiators and cross-linking agents used in UV-curable coatings, adhesives, and photoresists.
• Organic Methodology Development: A valuable tool for academic and industrial researchers exploring new C–I bond-forming reactions and catalytic cycles involving iodine.
• Fine Chemical Production: Applied in the custom synthesis of iodinated specialty chemicals and complex organic molecules for various high-value industrial applications.

Basic Information

Product Name	3-Oxo-3H-2,1-Benzoxiodolium Chloride
CAS No.	73698-48-3
Molecular Formula	C7H4ClIO2
Molecular Weight	282.46 g/mol
Synonyms	2-Iodobenzoic Acid Chloride Iodonium Salt; 1-Chloro-1,2-benziodoxol-3(1H)-one; 2-Iodobenzoyl Chloride, Cyclic Iodonium Salt; Benziodoxole Chloride; (Chloro)(2-carboxyphenyl)iodonium Chloride (inner salt); 1-Chloro-3-oxo-1,2-benziodoxole; Iodobenzoyl Chloride Cyclic Iodonium Salt
EINECS	Contact for details

Quality Control

Our 3-Oxo-3H-2,1-Benzoxiodolium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.