Description

1H-Indene-1-Carboxamide,2,3-Dihydro-,(R)-(9Ci) is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial Research: A valuable compound for methodological development in organic chemistry, including studies on stereoselective synthesis and molecular recognition.

Basic Information

Product Name	1H-Indene-1-Carboxamide,2,3-Dihydro-,(R)-(9Ci)
CAS No.	73392-00-4
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	(R)-2,3-Dihydro-1H-indene-1-carboxamide; (R)-1-Amino-2,3-dihydro-1H-indene-1-carboxylic acid amide; (R)-Indan-1-carboxamide; (R)-1-Carbamoylindane; (R)-1-Indanecarboxamide; (9CI) 1H-Indene-1-carboxamide, 2,3-dihydro-, (R)-; (R)-1,2,3,4-Tetrahydro-1-naphthamide (related structure); (R)-α-Aminoindane-1-carboxamide
EINECS	Contact for details

Quality Control

Our 1H-Indene-1-Carboxamide,2,3-Dihydro-,(R)-(9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.