Description

(+)-3-o-Phosphono-L-Glyceric Acid is a high-purity, chiral phosphonic acid derivative of glyceric acid, serving as a critical biochemical building block and enzyme inhibitor. This compound matters for its role in studying metabolic pathways, particularly those involving phosphoglycerate mutase and enolase, making it a valuable tool for biochemical research and pharmaceutical development. It is needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on enzymology, metabolic disorder research, and the synthesis of novel bioactive molecules.

Application

• Biochemical Research: Used as a substrate analog and potent inhibitor in studies of glycolytic enzymes, specifically phosphoglycerate mutase and enolase.
• Pharmaceutical Development: Serves as a key intermediate or pharmacophore in the research and synthesis of potential therapeutic agents targeting metabolic diseases.
• Enzymology Studies: Employed to investigate enzyme kinetics, mechanism of action, and structure-activity relationships (SAR) in carbohydrate metabolism.
• Diagnostic Reagent Manufacturing: May be utilized in the formulation of specialized diagnostic kits and assays for clinical or research laboratories.
• Fine Chemical Synthesis: Acts as a chiral synthon for the preparation of more complex, phosphorylated organic molecules and prodrugs.
• Academic Research: Essential for university and institutional research projects focused on cellular metabolism, bioenergetics, and signal transduction pathways.

Basic Information

Product Name	(+)-3-o-Phosphono-L-Glyceric Acid
CAS No.	73358-94-8
Molecular Formula	C3H7O7P
Molecular Weight	186.06 g/mol
Synonyms	L-(+)-3-Phosphonoglyceric Acid; (2R)-2-Hydroxy-3-(phosphonooxy)propanoic Acid; (R)-3-Phosphoglyceric Acid; PGAc; 3-PGA; 3-Phospho-L-glycerate; 3-Phosphoglycerate; Phosphoglyceric Acid
EINECS	Contact for details

Quality Control

Our (+)-3-o-Phosphono-L-Glyceric Acid is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.