Description

6-Oxabicyclo[3.1.0]Hexane-2-Ethanol,4,4-Difluoro-3-Hydroxy-,(1-α-,2-Bta-,3-Bta-,5-α-)-(9Ci) is a highly functionalized, chiral bicyclic ether compound that serves as a sophisticated synthetic intermediate. Its complex stereochemistry and the presence of fluorine and hydroxyl groups make it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atoms can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or cross-linking agent for synthesizing specialty polymers with unique thermal or chemical resistance properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and fluorine chemistry.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexane-2-Ethanol,4,4-Difluoro-3-Hydroxy-,(1-α-,2-Bta-,3-Bta-,5-α-)-(9Ci)
CAS No.	73313-51-6
Molecular Formula	C7H10F2O3
Molecular Weight	180.15 g/mol
Synonyms	(1α,2β,3β,5α)-4,4-Difluoro-3-hydroxy-6-oxabicyclo[3.1.0]hexane-2-ethanol; 4,4-Difluoro-3-hydroxy-6-oxabicyclo[3.1.0]hexane-2-ethanol; 6-Oxabicyclo[3.1.0]hexane-2-ethanol, 4,4-difluoro-3-hydroxy-, (1α,2β,3β,5α)-; Bicyclic fluorinated alcohol ether
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexane-2-Ethanol,4,4-Difluoro-3-Hydroxy-,(1-α-,2-Bta-,3-Bta-,5-α-)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation (NMR, IR) are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.