Description

(1R*,2S*,6R*,7S*,8R*)-8-Phenyl-4-Oxa-Tricyclo[5.2.1.0*2,6*]Decane-3,5-Dione is a high-purity, stereochemically defined tricyclic lactone building block of significant interest in advanced organic synthesis. This compound matters as a versatile chiral intermediate, enabling the construction of complex molecular architectures with precise three-dimensional control. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its rigid, functionalized structure contributes to biological activity.
• Asymmetric Catalyst Ligand Precursor: The defined stereocenters and functional groups make it a valuable starting material for synthesizing novel chiral ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that require specific, complex monomer units.
• Academic & Industrial R&D: A critical tool for methodological studies in organic chemistry, including studies on ring-opening reactions, cycloadditions, and stereoselective transformations.
• Fine Chemical Production: Acts as a building block for the synthesis of fragrances, flavors, and other high-value specialty chemicals requiring precise stereochemistry.

Basic Information

Product Name	(1R*,2S*,6R*,7S*,8R*)-8-Phenyl-4-Oxa-Tricyclo[5.2.1.0*2,6*]Decane-3,5-Dione
CAS No.	73252-09-2
Molecular Formula	C17H16O3
Molecular Weight	268.31 g/mol
Synonyms	8-Phenyl-4-oxatricyclo[5.2.1.0²,⁶]decane-3,5-dione; (±)-8-Phenyl-4-oxatricyclo[5.2.1.0²,⁶]decane-3,5-dione; rac-8-Phenyl-4-oxatricyclo[5.2.1.0²,⁶]decane-3,5-dione; 4-Oxa-tricyclo[5.2.1.0²,⁶]decane-3,5-dione, 8-phenyl-; TL-1-130; FCH-74163; SCHEMBL2180641; BCP31833
EINECS	Contact for details

Quality Control

Our (1R*,2S*,6R*,7S*,8R*)-8-Phenyl-4-Oxa-Tricyclo[5.2.1.0*2,6*]Decane-3,5-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% diastereomeric excess (d.e.)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.