Description

(R)-Benzo[1,3]Dioxol-5-Yl-tert-Butoxycarbonylamino-Acetic Acid is a high-purity chiral building block and protected amino acid derivative, essential for advanced pharmaceutical synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, ensuring the production of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is critically needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new drugs, particularly in areas like neurology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure APIs and investigational new drugs.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid derivative to introduce specific structural motifs.
• Asymmetric Synthesis: Serves as a precursor for catalysts or ligands used in stereoselective chemical transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the design of novel bioactive compounds.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-Benzo[1,3]Dioxol-5-Yl-tert-Butoxycarbonylamino-Acetic Acid
CAS No.	73101-12-9
Molecular Formula	C₁₄H₁₇NO₆
Molecular Weight	295.29 g/mol
Synonyms	(R)-N-[(1,3-Benzodioxol-5-yl)-N-(tert-butoxycarbonyl)]glycine; (R)-Boc-Pip-OH (contextual, for piperonylic acid derivative); (R)-3,4-(Methylenedioxy)benzyloxycarbonylamino-acetic acid, tert-butyl ester (related); BOC-DL-Pip; N-Boc-3,4-methylenedioxy-D-phenylglycine; (R)-N-(tert-Butoxycarbonyl)-2-(1,3-benzodioxol-5-ylamino)acetic acid; (R)-2-((1,3-Benzodioxol-5-yl)((tert-butoxycarbonyl)amino))acetic acid
EINECS	Contact for details

Quality Control

Our production of (R)-Benzo[1,3]Dioxol-5-Yl-tert-Butoxycarbonylamino-Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and cGMP-grade standards. A detailed Certificate of Analysis (COA) providing full specifications, including assay, enantiomeric excess, and impurity profiles, is provided with each shipment and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.