Description

8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxylic Acid 8-Methyl-Ethyl Ester is a specialized bicyclic organic compound that serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block in complex organic synthesis. Its unique bridged structure makes it invaluable for constructing complex molecular architectures with high stereochemical control. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of tropane alkaloid derivatives and other bioactive molecules with neurological or therapeutic activity.
• Chiral Synthesis: Employed as a stereodefined scaffold for constructing complex, enantiomerically pure compounds in asymmetric synthesis.
• Medicinal Chemistry Research: Used in drug discovery programs to explore new chemical space and develop structure-activity relationships (SAR).
• Agrochemical Development: Intermediate in the creation of novel pesticides or herbicides with specific modes of action.
• Catalyst Ligand Synthesis: Potential building block for creating novel ligands used in homogeneous catalysis.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic and heterocyclic chemistry.
• Custom Synthesis Projects: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxylic Acid 8-Methyl-Ethyl Ester
CAS No.	73045-45-1
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylic acid ethyl ester; Ethyl 8-methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate; 8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylic acid ethyl ester; Tropane derivative intermediate; 8-Azanortropene-2-carboxylic acid, 8-methyl-, ethyl ester; Ethyl 8-methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate; 73045-45-1; 8-Methyl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylic acid ethyl ester (ACI)
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Oct-2-Ene-2-Carboxylic Acid 8-Methyl-Ethyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.