Description

(4S)-4A,5,6,7,7A,8-Hexahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-4H-Indeno[5,6-B]Furan is a high-purity, complex bicyclic furan derivative with a defined stereochemistry, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its rigid, oxygenated framework makes it a valuable precursor for developing novel compounds with specific biological activities and material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fragrance industries who require sophisticated intermediates for creating high-value target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.
• Agrochemical Synthesis: Used as a building block in the creation of novel pesticides, herbicides, and plant growth regulators where its structural features can impart specific bioactivity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing unique odorants and flavor compounds, leveraging its complex, oxygenated terpene-like backbone.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and advanced materials due to its rigid, functionalized structure.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard in asymmetric synthesis and natural product total synthesis projects.
• Catalyst & Ligand Development: Potential use in the design of novel chiral ligands and organocatalysts for asymmetric transformations.

Basic Information

Product Name	(4S)-4A,5,6,7,7A,8-Hexahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-4H-Indeno[5,6-B]Furan
CAS No.	73020-90-3
Molecular Formula	C15H22O2
Molecular Weight	234.33 g/mol
Synonyms	(4S)-4a,5,6,7,7a,8-Hexahydro-4,4a,7,7a-tetramethyl-5,8-epoxy-4H-indeno[5,6-b]furan; (4S)-4a,5,6,7,7a,8-Hexahydro-4,4aβ,7β,7aβ-tetramethyl-5α,8α-epoxy-4H-indeno[5,6-b]furan; 4H-Indeno[5,6-b]furan, 4a,5,6,7,7a,8-hexahydro-4,4a,7,7a-tetramethyl-5,8-epoxy-, (4S)-; Ambretone; (S)-Ambrettolide epoxide isomer; A key intermediate for Ambrox derivatives
EINECS	Contact for details

Quality Control

Our production of (4S)-4A,5,6,7,7A,8-Hexahydro-4,4Aβ,7β,7Aβ-Tetramethyl-5α,8α-Epoxy-4H-Indeno[5,6-B]Furan adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.