Description

n-[(tert-Butoxycarbonyl)Amino]Methylamine Hydrochloride is a protected amine derivative, specifically a Boc-protected methylamine hydrochloride salt, widely used as a versatile building block in organic synthesis. Its primary value lies in providing a reactive amine group that is temporarily shielded from unwanted reactions, enabling precise and sequential molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and biotechnology sectors who require high-purity intermediates for peptide synthesis, linker chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used for introducing protected methylamine functionalities during solid-phase or solution-phase peptide assembly.
• Linker and Spacer Chemistry: Employed in the creation of molecular linkers for bioconjugation, prodrug development, and polymer chemistry.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of probes, inhibitors, and labeled compounds for biological studies.
• Material Science: Acts as a monomer or modifying agent in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	n-[(tert-Butoxycarbonyl)Amino]Methylamine Hydrochloride
CAS No.	73017-98-8
Molecular Formula	C7H16N2O2 • HCl
Molecular Weight	196.67 g/mol
Synonyms	Boc-NH-CH2-NH2 • HCl; (Boc-Amino)methylamine hydrochloride; 1-[(tert-Butoxycarbonyl)amino]methanamine hydrochloride; N-(tert-Butoxycarbonyl)methylenediamine hydrochloride; N-Boc-methylenediamine hydrochloride; tert-Butyl N-(aminomethyl)carbamate hydrochloride; 2-[(tert-Butoxycarbonyl)amino]ethan-1-amine hydrochloride (common misnomer); Boc-protected methylamine HCl
EINECS	Contact for details

Quality Control

Our n-[(tert-Butoxycarbonyl)Amino]Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.