Description

5-Chloro-3,4-Dihydroquinolin-2(1H)-One is a versatile and high-value heterocyclic organic compound, serving as a critical synthetic intermediate in advanced pharmaceutical and agrochemical research. Its core value lies in its functionalized quinolinone scaffold, which provides a privileged structure for constructing complex molecules with targeted biological activity. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides due to its bioactive quinolinone core.
• Organic Synthesis & Research: A versatile precursor for constructing complex heterocyclic systems and for methodological studies in organic chemistry.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and specialty polymers.
• Biochemical Tool Compound: Used in life science research to study enzyme inhibition and other biological pathways.

Basic Information

Product Name	5-Chloro-3,4-Dihydroquinolin-2(1H)-One
CAS No.	72995-15-4
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	5-Chloro-1,2,3,4-tetrahydroquinolin-2-one; 5-Chloro-3,4-dihydro-2(1H)-quinolinone; 5-Chloro-1,2,3,4-tetrahydro-2-quinolone; 5-Chloro-2-oxo-1,2,3,4-tetrahydroquinoline; 72995-15-4; 5-Chloro-3,4-dihydroquinolin-2-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-3,4-Dihydroquinolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available for every batch and provided upon request. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.