Description

n-Cyclopropyl-2-thioxo-1,2-dihydroquinoline-4-carboxamide is a specialized heterocyclic organic compound featuring a quinoline core modified with a thioxo group and a cyclopropylcarboxamide moiety. This unique structure makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing new chemical entities for biological screening and drug discovery.
• Chemical Reference Standard: Used as a high-purity standard in analytical method development and quality control laboratories.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the quinoline-thioxo-cyclopropyl motif into target molecules.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical and pharmacological studies.

Basic Information

Product Name	n-Cyclopropyl-2-thioxo-1,2-dihydroquinoline-4-carboxamide
CAS No.	72965-47-0
Molecular Formula	C₁₃H₁₂N₂OS
Molecular Weight	244.31 g/mol
Synonyms	4-Quinolinecarboxamide, N-cyclopropyl-1,2-dihydro-2-thioxo-; N-Cyclopropyl-2-mercaptoquinoline-4-carboxamide; 2-Thioxo-1,2-dihydroquinoline-4-carboxylic acid cyclopropylamide; 2-Mercapto-N-cyclopropylquinoline-4-carboxamide; Cyclopropyl 2-thioxo-1,2-dihydroquinoline-4-carboxamide; 72965-47-0; 4-Carbamoyl-2-mercaptoquinoline, N-cyclopropyl-
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-2-thioxo-1,2-dihydroquinoline-4-carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.