Description

8-Exo-Iodo-2-Azabicyclo[3.3.0]Octan-3-One is a high-value, bicyclic lactam building block featuring a strategically positioned iodine atom. This compound is critical for advanced organic synthesis, particularly in the construction of complex nitrogen-containing heterocycles and pharmacologically active scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive iodine handle for cross-coupling reactions.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex molecules, leveraging its rigid bicyclic structure.
• Agrochemical Synthesis: Acts as a building block for creating novel compounds with potential biological activity for crop protection.
• Academic Research: Utilized in methodological studies and the development of new synthetic transformations involving halogenated lactams.

Basic Information

Product Name	8-Exo-Iodo-2-Azabicyclo[3.3.0]Octan-3-One
CAS No.	72845-09-1
Molecular Formula	C7H10INO
Molecular Weight	251.07 g/mol
Synonyms	8-Iodo-2-azabicyclo[3.3.0]octan-3-one; 8-exo-Iodo-3-oxo-2-azabicyclo[3.3.0]octane; 2-Azabicyclo[3.3.0]octan-3-one, 8-iodo-; (3aR,6aS)-8-Iodo-2-azabicyclo[3.3.0]octan-3-one; 8-Iodo-3-oxo-2-azabicyclo[3.3.0]octane; Iodinated bicyclic lactam; 8-Iodo-2-aza-bicyclo[3.3.0]octan-3-one
EINECS	Contact for details

Quality Control

Our 8-Exo-Iodo-2-Azabicyclo[3.3.0]Octan-3-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.