Description

(E)-2-Methyl-2-Butenoic Acid [(3Ar,6R)-3,3Aβ,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-9-Methyl-3-Methylene-2,7-Dioxospiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-4α-Yl] Ester is a complex, high-purity synthetic intermediate characterized by its intricate spirocyclic and epoxy-functionalized structure. This compound matters as a critical building block for advanced pharmaceutical research and fine chemical synthesis, enabling the construction of novel molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for complex natural product analogs and targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its unique structure can contribute to specific biological activity.
• Fine Chemical Synthesis: Acts as a versatile scaffold for constructing complex molecules in academic and industrial research settings.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymeric or catalytic systems.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value chemical entities.

Basic Information

Product Name	(E)-2-Methyl-2-Butenoic Acid [(3Ar,6R)-3,3Aβ,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-9-Methyl-3-Methylene-2,7-Dioxospiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-4α-Yl] Ester
CAS No.	72782-53-7
Molecular Formula	C₂₀H₂₄O₅
Molecular Weight	344.40 g/mol
Synonyms	(E)-2-Methylbut-2-enoic acid [(3aR,6R)-3,3aβ,4,5,6aβ,7,9aβ,9bα-octahydro-9-methyl-3-methylene-2,7-dioxospiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-4α-yl] ester; Tiglic Acid [(3aR,6R)-3,3aβ,4,5,6aβ,7,9aβ,9bα-Octahydro-9-methyl-3-methylene-2,7-dioxospiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-4α-yl] Ester; 72782-53-7; Spiro[azuleno[4,5-b]furan-6(2H),2'-oxiran] ester derivative; (E)-2-Methyl-2-butenoic acid ester with a spiroazulenofuranoxiran
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-Butenoic Acid Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic confirmation are provided to guarantee identity, purity, and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert gas such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.