Description

9-Azabicyclo(3.3.1)Nonan-3-One Hydrochloride is a high-purity, nitrogen-containing bicyclic organic compound supplied as its hydrochloride salt. This specialized intermediate is critical for the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and receptor-based pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. The compound's unique bridged structure makes it a valuable scaffold in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Alkaloid Synthesis: Serves as a precursor in the laboratory synthesis of complex natural product analogs and tropane alkaloid derivatives.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and receptor binding.
• Fine Chemical Production: Integrated into multi-step synthesis processes for high-value, low-volume specialty chemicals.

Basic Information

Product Name	9-Azabicyclo(3.3.1)Nonan-3-One Hydrochloride
CAS No.	72761-60-5
Molecular Formula	C8H14ClNO
Molecular Weight	175.66 g/mol
Synonyms	3-Tropinone Hydrochloride; 9-Azabicyclo[3.3.1]nonan-3-one, hydrochloride; Tropinone HCl; 8-Methyl-8-azabicyclo[3.2.1]octan-3-one hydrochloride (common misnomer); Nortropinone hydrochloride; 3-Oxo-9-azabicyclo[3.3.1]nonane hydrochloride
EINECS	Contact for details

Quality Control

Our 9-Azabicyclo(3.3.1)Nonan-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, NMR, and other relevant techniques. Specifications are designed to meet the stringent requirements of pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.