Description

4,8-Dibromo-[1,6]Naphthyridine is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in the development of pharmaceuticals and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their R&D and scale-up activities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of new crop protection agents and herbicides, leveraging its halogenated naphthyridine core.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Employed in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized as a scaffold for developing fluorescent probes or molecular tags for biological imaging and diagnostic applications.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce the naphthyridine moiety into more complex systems.

Basic Information

Product Name	4,8-Dibromo-[1,6]Naphthyridine
CAS No.	72754-02-0
Molecular Formula	C8H4Br2N2
Molecular Weight	287.94 g/mol
Synonyms	4,8-Dibromo-1,6-naphthyridine; [1,6]Naphthyridine, 4,8-dibromo-; 4,8-Dibromonaphthyridine; 4,8-Dibromo-1,6-diazanaphthalene; Dibromo[1,6]naphthyridine; 72754-02-0 (CAS); 4,8-Dibromo-1,6-naphthyridine (IUPAC)
EINECS	Contact for details

Quality Control

Our 4,8-Dibromo-[1,6]Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports your regulatory and quality assurance requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.