Description

2-Pyrrolidinemethanol,1-Nitroso-,(R)-(9Ci) is a chiral, nitroso-substituted pyrrolidine derivative, a specialized organic intermediate of significant interest in advanced synthetic chemistry. Its value lies in its unique stereochemistry and functional groups, which make it a critical building block for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical development companies engaged in the synthesis of novel drug candidates, particularly in areas requiring precise stereochemical control. The CAS number for this compound is 72724-01-7.

Application

This chiral nitroso intermediate is utilized in sophisticated chemical synthesis across several high-value research and development sectors.

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets.
• Asymmetric Synthesis: Employed as a building block or chiral auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Agrochemical Development: Acts as an intermediate in the synthesis of novel, chiral pesticides or herbicides.
• Ligand Synthesis: Can be used to develop novel ligands for catalysis in organic transformations.
• Academic & Industrial R&D: Fundamental research in organic methodology development and the synthesis of complex natural product analogs.

Basic Information

Product Name	2-Pyrrolidinemethanol,1-Nitroso-,(R)-(9Ci)
CAS No.	72724-01-7
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(R)-1-Nitroso-2-pyrrolidinemethanol; (R)-1-Nitroso-2-(hydroxymethyl)pyrrolidine; (R)-N-Nitrosoprolinol; 1-Nitroso-L-prolinol; (R)-2-(Hydroxymethyl)-1-nitrosopyrrolidine; (R)-1-Nitroso-2-pyrrolidinylmethanol; 72724-01-7; (R)-Nitroso Prolinol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this high-purity research chemical, quality is assured through advanced analytical techniques including HPLC, chiral analysis, and NMR spectroscopy to confirm identity, enantiomeric purity, and chemical purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is light-sensitive (store away from light). Keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Yellow to orange solid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.