Description

2,3,4-Tri-o-Acetyl-α-D-Glucuronic Acid Methyl Ester is a key acetylated derivative of glucuronic acid, serving as a vital protected intermediate in synthetic organic chemistry. This compound is essential for researchers and manufacturers requiring precise control over glycosylation reactions and carbohydrate synthesis. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutics, prodrugs, and complex oligosaccharides.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Carbohydrate Chemistry Research: Used as a protected precursor in the study and synthesis of complex oligosaccharides, glycoconjugates, and heparin analogs.
• Bioconjugation: Enables the site-specific attachment of carbohydrate motifs to proteins, peptides, or other biomolecules for drug delivery and diagnostic applications.
• Glycosidase Inhibitor Development: Serves as a starting material or intermediate in the creation of enzyme inhibitors for biochemical research.
• Standards and Reference Materials: Provides a high-purity standard for analytical method development and quality control in related chemical processes.

Basic Information

Product Name	2,3,4-Tri-o-Acetyl-α-D-Glucuronic Acid Methyl Ester
CAS No.	72692-06-9
Molecular Formula	C15H20O12
Molecular Weight	392.31 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-α-D-glucopyranosyluronate); Methyl 2,3,4-tri-O-acetyl-α-D-glucopyranosiduronic acid; α-D-Glucopyranosiduronic acid, methyl 2,3,4-triacetate; Methyl 2,3,4-tri-O-acetyl-α-D-glucuronate; Triacetyl methyl glucuronate; Glucuronic acid methyl ester triacetate; 2,3,4-Tri-O-acetyl-α-D-glucuronic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-α-D-Glucuronic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.