Description

7,12-Dimethylbenz(A)Anthracene-10,11-Dihydrodiol is a high-purity, synthetic dihydrodiol derivative of the polycyclic aromatic hydrocarbon 7,12-dimethylbenz[a]anthracene (DMBA). This compound is a critical biochemical research standard and metabolic intermediate used to study carcinogenic mechanisms and metabolic pathways. It is essential for researchers and quality control laboratories in pharmaceutical development, toxicology, and environmental analysis who require precise and reliable reference materials.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in studies of polycyclic aromatic hydrocarbon (PAH) metabolism and activation pathways.
• Carcinogenicity Studies: Serves as a key metabolic intermediate for investigating the mechanisms of chemical carcinogenesis, particularly for its parent compound DMBA.
• Toxicology and Risk Assessment: Employed in in vitro and in vivo assays to evaluate the biological activity and toxicity of PAH metabolites.
• Pharmaceutical Development: Used in research related to chemoprevention and the development of compounds that inhibit the metabolic activation of procarcinogens.
• Analytical Method Development: Acts as a critical standard for calibrating analytical instruments like HPLC, GC-MS, and LC-MS in environmental and biological monitoring.
• Academic Research: Fundamental tool in university and institutional labs for teaching and advanced research in organic chemistry, biochemistry, and molecular biology.

Basic Information

Product Name	7,12-Dimethylbenz(A)Anthracene-10,11-Dihydrodiol
CAS No.	72471-79-5
Molecular Formula	C₂₀H₁₈O₂
Molecular Weight	290.36 g/mol
Synonyms	DMBA-10,11-dihydrodiol; 10,11-Dihydro-10,11-dihydroxy-7,12-dimethylbenz[a]anthracene; 7,12-DMBA-10,11-dihydrodiol; 7,12-Dimethylbenz[a]anthracene-10,11-diol; 10,11-Dihydroxy-10,11-dihydro-7,12-dimethylbenz[a]anthracene; (+/-)-10,11-Dihydroxy-10,11-dihydro-7,12-dimethylbenz[a]anthracene; anti-7,12-Dimethylbenz[a]anthracene-10,11-dihydrodiol
EINECS	Contact for details

Quality Control

Our 7,12-Dimethylbenz(A)Anthracene-10,11-Dihydrodiol is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, spectroscopic identification (NMR, IR), and mass confirmation. A detailed Certificate of Analysis (COA) providing full analytical data is supplied with every shipment to support your regulatory compliance and research integrity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.